山东大学教师主页鞠俊 Paper Publications Home

Associate Professor

山东大学基础医学院副研究员，2013年本科毕业于四川大学，2019年博士毕业于北京大学，多年来从事神经系统疾病的机制研究，包括自闭症以及精神分裂症。以第一作者或通讯作者（含共同）在Molecular Psychiatry, PNAS, Advanced Science和PROG NEURO-PSYCHOPH等SCI期刊上发表10余篇论文，主持国家基金委-青年项目和广东省区域联合基金-青年项目各1项。最近的研究发现，40赫兹闪光或者干预CD47，可以改善16p11.2缺失自闭症小鼠模型的E-I失衡以及行为学缺陷。 More+

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Paper Publications

[2] Jun Ju, Yifan Pan, Xinyi Yang, Xuanyi Li, Jinghong Chen, Shiyu Wu, Sheng-Tao Hou*.. The "don’t eat me" signal CD47 is associated with microglial phagocytosis defects and autism-like behaviors in 16p11.2 deletion mice. Proc Natl Acad Sci U S A. 2025 Apr 22;122(16):e2411080122.,

[4] Jun Ju, Luping Liu, Yujie Zhang, Qiang Zhou*. Effect of age onset on schizophrenia-like phenotypes and underlying mechanisms in model mice.. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:465-474.,

[5] Jun Ju#, Luping Liu#, Xinyi Yang, Siqi Men, Sheng-Tao Hou*. Distinctive effects of NMDA receptor modulators on cerebral microcirculation in a schizophrenia mouse model.. Biochemical and Biophysical Research Communications 653 (2023) 62-68,

[6] Luping Liu, Tianxiang Li, Jinlong Chang, Xiaojiao Xia, Jun Ju*. Microglia inversely regulate the level of perineuronal nets with the treatment of lipopolysaccharide and valproic acid. Neurosci Lett. 2024 Sep 18;:137992,

[7] Luping Liu, Yujie Zhang, Jun Ju*. Removal of perineuronal nets leads to altered neuronal excitability and synaptic transmission in the visual cortex with distinct time courses. Neurosci Lett. 2022 Aug 10;785:136763,

[8] Luping Liu#, Yujie Zhang#, Siqi Men, Xuanyi Li, Sheng-Tao Hou, Jun Ju. Elimination of perineuronal nets in CA1 disrupts GABA release and long-term contextual fear memory retention. Hippocampus. 2023 Jul;33(7):862-871,

[9] Jian Jiang#, Jun Ju#, Liang Luo# et.al, Huiliang Li* and Ningning Li*. Salmon Calcitonin Exerts an Antidepressant Effect by Activating Amylin Receptors. Front Pharmacol. 2022 Feb 14:13:826055,

[10] Jin Zhang#, Weifen Li#, Qi Yue, Luping Liu, Sheng-Tao Hou, Jun Ju. Rapamycin exerts an antidepressant effect and enhances myelination in the prefrontal cortex of chronic restraint stress mice. Neuroscience. 2023 Nov 4;535:99-107,

[11] Jun Ju#, Xiuyan Yang#, Jian Jiang# et.al, Huiliang Li, Ningning Li. Structural and lipidomic alterations of striatal myelin in 16p11.2 deletion mouse model of autism spectrum disorder. Front Cell Neurosci. 2021;15:718720,

[12] Jun Ju#, Qian Liu#, Yang Zhang et.al Hedong Li*. Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum. Sci Rep. 2016 Jul 29;6:30711,

Paper Publications

[2] Jun Ju, Yifan Pan, Xinyi Yang, Xuanyi Li, Jinghong Chen, Shiyu Wu, Sheng-Tao Hou*.. The "don’t eat me" signal CD47 is associated with microglial phagocytosis defects and autism-like behaviors in 16p11.2 deletion mice. Proc Natl Acad Sci U S A. 2025 Apr 22;122(16):e2411080122.,

[4] Jun Ju, Luping Liu, Yujie Zhang, Qiang Zhou*. Effect of age onset on schizophrenia-like phenotypes and underlying mechanisms in model mice.. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:465-474.,

[5] Jun Ju#, Luping Liu#, Xinyi Yang, Siqi Men, Sheng-Tao Hou*. Distinctive effects of NMDA receptor modulators on cerebral microcirculation in a schizophrenia mouse model.. Biochemical and Biophysical Research Communications 653 (2023) 62-68,

[6] Luping Liu, Tianxiang Li, Jinlong Chang, Xiaojiao Xia, Jun Ju*. Microglia inversely regulate the level of perineuronal nets with the treatment of lipopolysaccharide and valproic acid. Neurosci Lett. 2024 Sep 18;:137992,

[7] Luping Liu, Yujie Zhang, Jun Ju*. Removal of perineuronal nets leads to altered neuronal excitability and synaptic transmission in the visual cortex with distinct time courses. Neurosci Lett. 2022 Aug 10;785:136763,

[8] Luping Liu#, Yujie Zhang#, Siqi Men, Xuanyi Li, Sheng-Tao Hou*, Jun Ju*. Elimination of perineuronal nets in CA1 disrupts GABA release and long-term contextual fear memory retention. Hippocampus. 2023 Jul;33(7):862-871,

[9] Jian Jiang#, Jun Ju#, Liang Luo# et.al, Huiliang Li* and Ningning Li*. Salmon Calcitonin Exerts an Antidepressant Effect by Activating Amylin Receptors. Front Pharmacol. 2022 Feb 14:13:826055,

[10] Jin Zhang#, Weifen Li#, Qi Yue, Luping Liu, Sheng-Tao Hou*, Jun Ju*. Rapamycin exerts an antidepressant effect and enhances myelination in the prefrontal cortex of chronic restraint stress mice. Neuroscience. 2023 Nov 4;535:99-107,

[11] Jun Ju#, Xiuyan Yang#, Jian Jiang# et.al, Huiliang Li*, Ningning Li*. Structural and lipidomic alterations of striatal myelin in 16p11.2 deletion mouse model of autism spectrum disorder. Front Cell Neurosci. 2021;15:718720,

[12] Jun Ju#, Qian Liu#, Yang Zhang et.al Hedong Li*. Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum. Sci Rep. 2016 Jul 29;6:30711,

[8] Luping Liu#, Yujie Zhang#, Siqi Men, Xuanyi Li, Sheng-Tao Hou, Jun Ju. Elimination of perineuronal nets in CA1 disrupts GABA release and long-term contextual fear memory retention. Hippocampus. 2023 Jul;33(7):862-871,

[10] Jin Zhang#, Weifen Li#, Qi Yue, Luping Liu, Sheng-Tao Hou, Jun Ju. Rapamycin exerts an antidepressant effect and enhances myelination in the prefrontal cortex of chronic restraint stress mice. Neuroscience. 2023 Nov 4;535:99-107,

[11] Jun Ju#, Xiuyan Yang#, Jian Jiang# et.al, Huiliang Li, Ningning Li. Structural and lipidomic alterations of striatal myelin in 16p11.2 deletion mouse model of autism spectrum disorder. Front Cell Neurosci. 2021;15:718720,